Table 2.
Genotype and alcohol consumption | eGFR (ml/min/1.73 m2) | eGFR † (ml/min/1.73 m2) | eGFR ‡ (ml/min/1.73 m2) |
---|---|---|---|
Mt5178C (N = 239) |
|
|
|
Non-drinkers (N = 44) |
75.8 ± 2.0 |
76.5 ± 1.9 |
74.5 ± 2.3 |
Occasional drinkers (N = 84) |
81.8 ± 1.4* |
81.1 ± 1.3 |
79.1 ± 1.9 |
Daily drinkers (N = 111) |
78.4 ± 1.2 |
78.6 ± 1.2 |
76.8 ± 1.6 |
|
P for trend = 0.667 |
P for trend = 0.693 |
P for trend = 0.612 |
Mt5178A (N = 155) |
|
|
|
Non-drinkers (N = 21) |
74.3 ± 2.6 |
75.8 ± 2.6 |
75.8 ± 3.0 |
Occasional drinkers (N = 60) |
81.3 ± 1.6 |
81.0 ± 1.5 |
80.8 ± 2.1 |
Daily drinkers (N = 74) |
83.8 ± 1.4** |
83.6 ± 1.4* |
83.7 ± 2.0* |
P for trend = 0.003 | P for trend = 0.009 | P for trend = 0.008 |
eGFR; estimated glomerular filtration rate. †eGFR is given as least-square mean ± S.E. adjusted for age, body mass index; ‡eGFR is given as least-square mean ± S.E. adjusted for age, body mass index, habitual smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was used. *P < 0.05 vs. non-drinkers, **P < 0.01 vs. non-drinkers.