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. 2013 Feb 12;14:35. doi: 10.1186/1471-2369-14-35

Table 2.

Estimated glomerular filtration rates by alcohol consumption and Mt5178 C/A genotype

Genotype and alcohol consumption eGFR (ml/min/1.73 m2) eGFR † (ml/min/1.73 m2) eGFR ‡ (ml/min/1.73 m2)
Mt5178C (N = 239)
 
 
 
Non-drinkers (N = 44)
75.8 ± 2.0
76.5 ± 1.9
74.5 ± 2.3
Occasional drinkers (N = 84)
81.8 ± 1.4*
81.1 ± 1.3
79.1 ± 1.9
Daily drinkers (N = 111)
78.4 ± 1.2
78.6 ± 1.2
76.8 ± 1.6
 
P for trend = 0.667
P for trend = 0.693
P for trend = 0.612
Mt5178A (N = 155)
 
 
 
Non-drinkers (N = 21)
74.3 ± 2.6
75.8 ± 2.6
75.8 ± 3.0
Occasional drinkers (N = 60)
81.3 ± 1.6
81.0 ± 1.5
80.8 ± 2.1
Daily drinkers (N = 74)
83.8 ± 1.4**
83.6 ± 1.4*
83.7 ± 2.0*
  P for trend = 0.003 P for trend = 0.009 P for trend = 0.008

eGFR; estimated glomerular filtration rate. †eGFR is given as least-square mean ± S.E. adjusted for age, body mass index; ‡eGFR is given as least-square mean ± S.E. adjusted for age, body mass index, habitual smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was used. *P < 0.05 vs. non-drinkers, **P < 0.01 vs. non-drinkers.