Table 3.
Enriched functional group in GCMN
| Functional group | Group Genes | GOID | % Genes1 | p-Value2 | p-Value/B3 |
|---|---|---|---|---|---|
| Cell cycle |
ANXA1|SFN|YWHAB|YWHAE|YWHAG|YWHAQ|YWHAZ |
KEGG:04110 |
5.0 |
9.00E-07 |
4.77E-05 |
| Phospholipase inhibitor activity |
ANXA1|ANXA2|ANXA5|ARHGDIA|ATP5B|KRT1 |
GO:0004859 |
27.3 |
3.17E-06 |
1.68E-04 |
| Melanosome |
ANXA1|ANXA2|ANXA5|ATP5B|CLIC1|CTSD|FASN|HRNR|HSP90AA1|HSP90AB1|HSPA1B|HSPA8|HSPB1|KRT1|PDIA3|RAC1|SFN|YWHAB|YWHAE|YWHAG|YWHAZ |
GO:004247 |
12.8 |
4.09E-16 |
2.17E-14 |
| Neurotrophin signaling pathway |
ACTB|ARHGDIA|CAPZA1|CAPZB|CDC42|HSPB1|MYLK|RAC1|SFN|YWHAB|YWHAE|YWHAG|YWHAQ|YWHAZ |
KEGG:04722 |
6.1 |
2.36E-09 |
1.25E-07 |
| Downregulated of MTA-3 in ER-negative breast tumors |
ADH1B|ALDOA|CTSD|ECH1|HSPB1|PHGDH|RYR3 |
BioCarta:204 |
28.6 |
4.94E-08 |
2.62E-06 |
| Glycolysis/Gluconeogenesis | ADH1B|ALDOA|ECH1|FASN | KEGG:00010 | 4.7 | 7.23E-04 | 0.038 |
1% of associated genes identified in our results/total known genes involved in the function or pathway, 2Term p-Value, 3Term p-Value with Bonferroni correction.