Table 1.
Effects of PF on body weight and main organs weight in DMN-induced rat liver fibrosis ( )
| Group (number) | Body weight (g) | Liver weight (g) | Spleen weight (g) | Heart weight (g) | Lung weight (g) | Kidney weight (g) | Brain weight (g) |
|---|---|---|---|---|---|---|---|
| 2-week normal(3) |
199.33±9.45 |
6.81±0.61 |
0.54±0.11 |
0.56±0.09 |
0.75±0.12 |
1.16±0.10 |
1.04±0.02 |
| 2-week DMN(3) |
180.33±0.55 |
7.67±0.47 |
0.77±0.06⋆ |
0.50±0.01▴ |
0.93±0.06⋆ |
1.37±0.06 |
1.10±0.00 |
| 4-week normal(7) |
273.90±12.29▴ |
10.03±0.86▴ |
0.59±0.09⋆ |
0.81±0.07▴ |
1.00±0.00 |
1.64±0.15▴ |
1.17±0.05 |
| DMN-water(5) |
201.50±17.81 |
5.92±1.64 |
1.38±0.30☆ |
0.72±0.07△ |
1.05±0.11☆ |
1.43±0.08 |
1.20±0.10 |
| DMN-PF(7) |
208.87±18.46 |
6.45±1.21 |
1.13±0.22 |
0.66±0.05 |
1.00±0.00 |
1.46±0.13 |
1.17±0.05 |
| DMN-GdCl3(6) | 183.48±13.99▴ | 4.73±0.41 | 1.11±0.08 | 0.63±0.08▴ | 1.07±0.10 | 1.65±0.26▴ | 1.13±0.12 |
△p<0.05 versus the same period in 2-week DMN rats; ▴p<0.05 versus the same period in DMN-water rats.
Bonferroni’s multiple comparison test were used for group comparisons in body weight, liver weight, heart weight, and kidneys weight.
☆p<0.05 versus the same period in 2-week DMN rats; ⋆p<0.05 versus the same period in DMN-water rats. Kruskal-Wallis test were used for group comparisons in liver weight, spleen weight, lung weights, and brain weight.