Figure 1. Effects of Sterol Pathway Inhibitors on EBOV Infection.

Dose response curves for the indicated sterol pathway inhibitors are shown. The compounds were evaluated, in parallel at the indicated concentrations, for their ability to inhibit EBOV infection (black) and for inhibition of cell proliferation (gray) in Vero cells. The maximal % inhibition and the IC₅₀ (µM) for their effects on EBOV infection are indicated. Data for clomiphene are presented in Johansen, et al. (manuscript in preparation).