Table 1. Case-control association for genotyped variants in AA and EA.
SNP | Position | Alleles | AA | EA | ||||||
Affected | Control | P-value | OR | Affected | Control | P-value | OR | |||
(N = 1525) | (N = 4485) | [95%CI] | (N = 3968) | (N = 9750) | [95%CI] | |||||
rs13023380 | 162,862,609 | G/A | 0.885 | 0.911 | 4.33×10−5 + | 0.75 | 0.433 | 0.478 | 9.52×10−11 + | 0.84 |
3.92×10−4 * | (0.66–0.86) | 6.66×10−11 * | (0.79–0.88) | |||||||
1.75×10−2 ** | 8.71×10−11 ** | |||||||||
rs10930046 | 162,846,229 | G/A | 0.374 | 0.428 | 1.81×10−7 + | 0.80 | 0.016 | 0.013 | 8.61×10−2 + | 1.21 |
3.22×10−6 * | (0.73–0.87) | 8.4×10−2 * | (0.97–1.50) | |||||||
8.51×10−6 ** | 0.12** | |||||||||
rs1990760 | 162,832,297 | G/A | 0.799 | 0.829 | 2.02×10−4 + | 0.82 | 0.375 | 0.400 | 1.22×10−4 + | 0.90 |
2.61×10−3 * | (0.74–0.91) | 1.44×10−4 * | (0.85–0.95) | |||||||
1.43×10−2 ** | 1.74×10−4 ** |
The numbers of affected and control samples are provided in parentheses. Allele frequencies, odds ratios (OR), and 95% confidence intervals [95% CI] are given for the ‘G’ alleles. Allelic association legends are:
uncorrected;
corrected by local ancestry; and
corrected by global ancestry.