Table 1.

Summary of findings from studies of first-episode psychosis treatment with or without specialized substance abuse treatment

Study	Substance use outcome	Mental health outcome	Functional outcome
Without specialized substance abuse treatment
Archie et al., 2007 (11)	Improvementa	No change	No change
Baeza et al., 2009 (43)	Mixed findings	Improvement	Not assessed
Grech et al., 2005 (5)	Improvement	Mixed findings	Not assessed
Harrison et al., 2008 (44)	Improvement	Mixed findings	No change
Kovasznay et al., 1997 (7)	Observational only	No change	Observational only
Lambert et al., 2005 (24) and Hinton et al., 2007 (45)	Improvement	Improvement	Not assessed
Turkington et al., 2009 (46)	Improvement	Observational only	Observational only
Verdoux et al., 2001 (47)	Improvement	Not assessed	Not assessed
With specialized substance abuse treatment
Addington et al., 2001 (48)	Improvement	No change	Mixed findings
Carr et al., 2009 (49)	Improvement	Not assessed	Not assessed
Edwards et al., 2006 (50)	No change	No change	No change
Gleeson et al., 2009 (51)	No change	Improvement	No change
Kavanagh et al., 2004 (52)	No change	Not assessed	Not assessed

^a“Improvement” indicates the intervention group demonstrated a statistically significant increase in positive outcomes or a decrease in negative outcomes compared with the comparison or control group. “Mixed findings” indicates improvement on some measures of the outcome and no difference or negative findings on other measures of the outcome. [For additional information, see online appendix at ps.psychiatryonline.org.]