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. 2013 Jan 25;190(5):2208–2216. doi: 10.4049/jimmunol.1200322

FIGURE 3.

FIGURE 3.

Absence of Fer kinase enhances chemotaxis toward end target, but not intermediate chemoattractants in vitro. In vitro neutrophil chemotaxis, determined using the under-agarose gel assay using bone marrow–derived neutrophils from WT (open bars) and Fer mutant mice (FerDR/DR; solid bars). (A) Illustrates the number of chemotactic cells in response to increasing concentrations of WKYMVm (0.01–100 μM). Data are expressed as mean ± SEM, 10–24 plates (n = 5 mice). (B) Illustrates the number of chemotactic cells in response to increasing concentrations of KC (0.0125–125 μM). Data are expressed as mean ± SEM, 9–12 plates (n = 3 mice). (C) Illustrates the number of chemotactic cells in response to increasing concentrations of LTB4 (0.01–100 μM). Data are expressed as mean ± SEM, 9–12 plates (n = 3 mice). *p < 0.05 significant increase over WT neutrophils.