Table I. Hemodynamic parameters in WT, Fer mutant (FerDR/DR), and FerDR/DR chimeric mice under control conditions.
WT | FerDR/DR | Endo-FerDR/DR Chimeras | Leuk-FerDR/DR Chimeras | |
---|---|---|---|---|
Vessel diameter (μm) | 32.0 ± 0.8 | 30.8 ± 1.5 | 33.1 ± 2.3 | 32.0 ± 1.0 |
RBC velocity (mms−1) | 5.0 ± 0.5 | 3.3 ± 0.2 | 3.2 ± 0.4 | 3.5 ± 0.3 |
Data are expressed as the mean ± SEM. n = 4 (WT), n = 5 (FerDR/DR), n = 4 (endothelium-FerDR/DR), n = 4 (leukocyte-Fer). For each group, values were taken immediately prior to agarose gel placement on the extravascular tissue. Data were not significantly different immediately postgel placement (data not shown).