Table III. Fes kinase does not contribute to LTB₄-induced chemotaxis.

	Number of Chemotactic Cells
	WKYMVm	LTB4
Wild type	48.9 ± 8.3	51.9 ± 6.1
FerDR/DR	102.7 ± 15.1*	63.1 ± 7.4
FesKR/KR/FerDR/DR	159.0 ± 33.4*	72.1 ± 9.6

Neutrophil chemotaxis was determined in vitro using the under-agarose gel assay. Chemotaxis was determined in response to WKYMVm (1 μM) or LTB₄ (1 μM) using bone marrow–derived neutrophils from wild-type, Fer mutant (Fer^DR/DR), or Fps/Fer double-mutant mice (Fes^KR/KR/Fer^DR/DR). Data are expressed as mean ± SEM, 23–24 plates (n = 3 mice).

^*p < 0.05 significantly different from WT neutrophils.