Figure 5.
Expression of D1R-, D2R-, A2aR-, and D3R-containing MSNs in subterritories of the caudomedial NAc shell. (A) Percentage of DARPP-32-positive neurons expressing GFP in Drd1a-EGFP, Drd2-EGFP, and Drd3-Cre mice in bundle-shaped area of the caudomedial NAc shell. Quantifications were obtained from several images. Total number of MSNs counted: n = 950 MSNs in Drd1a-EGFP (eight hemispheres from four mice), n = 898 MSNs in Drd2-EGFP (eight hemispheres from four mice), and n = 629 MSNs in Drd3-Cre (eight hemispheres from two mice). The table summarizes the surface area analyzed for each mouse line. (B) Percentage of DARPP-32-positive neurons expressing GFP in Drd1a-EGFP, Adora2a-Cre, and Drd3-Cre mice in the D2R-expressing MSNs-poor zone of the caudomedial NAc shell. Quantifications were obtained from several images. Total number of MSNs counted: n = 329 MSNs in Drd1a-EGFP (six hemispheres from three mice), n = 349 MSNs in Adora2-Cre (six hemispheres from three mice), and n = 365 MSNs in Drd3-Cre (eight hemispheres from two mice). The table summarizes the surface area analyzed for each mouse line.
