Table 1.
Clinical characteristics and anthropometric measurements of the study population.
| T1DM (n=26) 9 prepubertal |
OBESE (n=24) 8 prepubertal |
CONTROLS (n= 21) 8 prepubertal |
P value | |
|---|---|---|---|---|
| Age (years) | 12.62 ± 2.43 | 13.07 ± 2.04 | 12.19 ± 2.67 | ns |
| Gender Ratio | 0.8 : 1 | 1 : 1 | 1.1 : 1 | ns |
| Weight (Kg) | 47.76 ± 12.74 | 74.28 ± 24.47† | 48.22 ± 8.68 | <0.0001 |
| Height (cm) | 153.4 ± 15.13 | 152.54 ± 3.01 | 150.37 ± 11.75 | ns |
| BMI (Kg/m2) | 19.93 ± 2.74 | 31.02 ± 4.96† | 21.18 ± 2.33 | <0.0001 |
| SBP (mmHg) | 113.65 ± 2.28* | 117.3 ± 2.38* | 107 ± 2.54 | <0.015 |
| DBP (mmHg) | 73.26 ± 10.29* | 74.16 ± 13.32* | 64.04 ± 3.39 | <0.002 |
| Blood Glucose (mg/dl) | 186.69 ± 98.54π | 80.03 ± 10.71 | 79.15 ± 9.04 | <0.0001 |
| Insulinemia 0' (µu/ml) | 0.74 ± 0,28 | 32.2 ± 14.2 | - | - |
| Insulinemia 120' (µu/ml) | - | 141.2 ± 56.54 | - | - |
| Total cholesterol (mg/dl) | 157.25 ± 27.95 | 163.52 ± 30.81 | - | - |
| HDL cholesterol (mg/dl) | 50.17 ± 11.14 | 47.46 ± 9.57 | - | - |
| LDL cholesterol (mg/dl) | 90.14 ± 19.47 | 101.12 ± 24.72 | - | - |
| Tryglicerides (mg/dl) | 54.00 ± 21.20 | 84.58 ± 37.25† | 57.24 ± 19.16 | <0.001 |
| HbA1C (%) | 7.99 ± 1.71 | - | - | - |
| CRP (mg/dl) | 1.71 ± 1.85 | 3.64 ± 2.60† | 1 ± 0.62 | <0.001 |
Parameters are shown as averages ± standard deviation; BMI: body mass index; SPB: systolic blood pressure; DPB: diastolic blood pressure, HDL: high density level; LDL: low density level; CRP: C-reactive protein. *p value <0.05 vs controls. †p value <0.05 vs T1DM and controls. πp value <0.05 vs obese and controls.