Table 2.
Decreased protein synthesis and increased protein degradation contribute to decreased protein expression in SKBR3_shVPS4B cells.
| Number of proteins* | Percentage (%) | |
|---|---|---|
| Decreased synthesis only | 7 | 18.4 |
| Increased degradation only | 6 | 15.8 |
| Both | 25 | 65.8 |
*Number of proteins was calculated from 38 proteins with decreased relative abundance (SKBR3_shVPS4B versus SKBR3 ratio <0.66) at 24 hr.