Figure 1.
CARs in naturally intronless mRNAs contain a conserved motif. (A) The 10-nt consensus element (CAR-E) identified in the CARs from HSPB3, c-Jun, IFNα1 or IFNβ1 is shown. (B) The locations of the CAR-Es in each CAR are indicated by the boxes. The height of box is proportional to −log(P-value), truncated at the height for a motif with a P-value of 1 × 10−10 (34). The numbering is relative to the first nucleotide of each CAR sequence. (C) The sequences of each of the CAR-Es (colored bases) surrounded by flanking sequence (black bases) are shown.