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. 2013 Jan 7;41(4):2736–2745. doi: 10.1093/nar/gks1321

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.

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Figure 4. — The two TFIIH-binding regions of Rad4 are crucial for survival following UV irradiation. (a) The survival of RAD4 (blue), rad4-PP (black) and rad4-AAA yeast were determined following increasing doses of UV irradiation. (b) The survival of RAD4 (blue), rad4 (red), rad4-PP (black), rad4-AAA (orange) and rad4-PPAAA (aqua) yeast were determined following increasing doses of UV irradiation. In both (a) and (b), the y-axis represents the percentage of surviving cells (normalized to the number of viable cells not exposed to UV light) and the x-axis shows the energy levels of the UV irradiation applied (J/m²). The results are the mean ± SEM of three independent experiments.