Figure 3.

Percentage distribution of Alu mediated events across the transcripts. In terms of base pair coverage, >88% of Alu exonization primarily occurs in the 3′UTR region with a small fraction in 5′UTR and a minimal fraction in the CDS region. Surprisingly, the 3′UTR is enriched in both antisense and A→I events. The coordinates for Alu antisense events were anchored on Alu-harbouring exons across the CDS and UTR regions. For a normalized count, percentage contribution to Alu antisense in each of the three regions is expressed as fraction of the Alu-harbouring exons that overlap with antisense coordinates. Percentage contribution to Alu editing in each of the UTR or CDS region is expressed as fraction of the Alu-harbouring exons that have occurrence of A→I editing events.