Figure 1.

Schematic of vimentin molecular structure. Panel (A) shows a representation of the protein domains of vimentin. At the amino terminus is the head domain, leading into rod domain 1. The black box between rod 1B and rod 2B represents Linker 1–2. The dark gray box between rod 1B and rod 2B represents the parallel helices structure of rod 2A/Linker 2. Panel (B) shows the amino acid sequence of the tail domain, beginning with Y⁴⁰⁰. The HTM and β (beta) sites are boxed and labeled. Prolines are in bold; phosphorylation sites are indicated by asterisks.