Table 2.
Differentially expressed genes in Cluster 6
| Symbol | Gene | Fold changea | |||
|---|---|---|---|---|---|
| Inflamed | iLP | iLP(A−) | iBL23 | ||
| IL17A | Interleukin 17A | 14.3 | 6.9 | 5.6 | 5.9 |
| CXCL11 | Chemokine (C-X-C motif) ligand 11 | 10.9 | 4.2 | 6.6 | 3.1 |
| IFNG | Interferon, gamma | 10.5 | 5.9 | 4.8 | 4.4 |
| CXCL9 | Chemokine (C-X-C motif) ligand 9 | 9.9 | 3.0 | 3.5 | 2.4 |
| IL2 | Interleukin 2 | 9.5 | 2.2 | 2.2 | 2.8 |
| XCL1 | Chemokine (C motif) ligand 1 | 7.7 | 4.3 | 3.3 | 4.1 |
| GZMB | Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 6.5 | 2.3 | 3.2 | 2.6 |
| TNFRSF9 | Tumor necrosis factor receptor superfamily, member 9 | 4.5 | 1.9 | 2.3 | 1.6 |
| INDO | Indoleamine-pyrrole 2,3 dioxygenase | 4.5 | 1.8 | 1.3 | 1.6 |
| XIRP1 | Xin actin-binding repeat containing 1 | 4.4 | 2.8 | 2.7 | 2.2 |
| RNF19B | Ring finger protein 19B | 4.2 | 1.3 | 2.2 | 1.6 |
| ZBED2 | Zinc finger, BED-type containing 2 | 3.7 | 2.4 | 1.7 | 1.9 |
| GBP1 | Guanylate-binding protein 1, interferon-inducible, 67 kDa | 3.5 | 2.0 | 1.6 | 2.0 |
| IRF1 | Interferon regulatory factor 1 | 3.2 | 2.5 | 2.9 | 2.4 |
| CRTAM | Cytotoxic and regulatory T cell molecule | 3.2 | 2.3 | 1.7 | 2.1 |
| CD226 | CD226 molecule | 3.0 | 1.4 | 1.6 | 1.5 |
| ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3 | 3.0 | 1.4 | 1.9 | 1.6 |
| GBP4 | Guanylate-binding protein 4 | 2.9 | 1.6 | 1.6 | 1.3 |
| UBD | Ubiquitin D | 2.9 | 2.2 | 2.4 | 1.9 |
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 2.9 | 1.8 | 1.3 | 2.2 |
| IL2RA | Interleukin 2 receptor, alpha | 2.7 | 2.1 | 1.7 | 2.0 |
| TNFRSF4 | Tumor necrosis factor receptor superfamily, member 4 | 2.7 | 1.8 | 1.5 | 1.6 |
| ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 2.7 | 1.6 | −1.1 | 1.6 |
| EGR2 | Early growth response 2 | 2.6 | 2.1 | 2.3 | 2.0 |
| GBP2 | Guanylate-binding protein 2, interferon-inducible | 2.1 | 1.9 | 2.0 | 1.8 |
| IRF1 | Interferon regulatory factor 1 | 2.4 | 2.3 | 2.6 | 2.3 |
| GJA4 | Gap junction protein, alpha 4, 37 kDa | 2.3 | 2.0 | 2.7 | 2.1 |
| DUOX1 | Dual oxidase 1 | 2.1 | 1.3 | 1.4 | 1.8 |
| STK19 | Serine/threonine kinase 19 | 2.1 | 1.3 | 1.2 | 1.4 |
| CPN1 | Carboxypeptidase N, polypeptide 1 | 2 | 1.5 | 1.3 | 1.7 |
| CTSS | Cathepsin S | 2.0 | 1.3 | 1.3 | 1.1 |
| CYB561 | Cytochrome b-561 | 1.9 | 1.3 | 1.9 | 1.4 |
| PPP1R11 | Protein phosphatase 1, regulatory (inhibitor) subunit 11 | 1.8 | 1.0 | 1.2 | 1.1 |
aFold changes are expressed relative to Control