Table 2.

Genome-wide association scans performed utilising high genome coverage and large cohorts

Study	Ethnicity of discovery cohort and cohort size	Ethnicity of replication cohort and overall cohort size for discovery and replication combined	Outcome	Refs
Rotterdam	European – Netherlands 1341 cases and 3496 controls	European and North American of European descent 14 938 cases and 39 000 controls	One signal, at chromosome 7q22	21
Tokyo	Asian – Japanese 899 cases and 3396 controls	Asian and European 1879 cases and 3396 controls	One signal, at the HLA locus	22
arcOGEN	European – UK 3177 cases and 4894 controls	European and North American of European descent 13 768 cases and 53 286 controls	Three signals	23
	European – UK 7410 cases and 11 009 controls	European 14 883 cases and 53 947 controls	Eight signals	24