Fig. 2.

TUBB3 knockdown sensitizes gastric cancer cells to paclitaxel. (A) Western blot analysis of TUBB3 in AGS cells without treatment or in the presence of si-scramble control or si-TUBB3 RNAs. Actin was used as a loading control. (B) AGS cells were treated with si-scramble or si-TUBB. Cells were maintained in normoxia or hypoxia for 24 h with paclitaxel. Cell proliferation was normalized to the normoxic control. Values are expressed as means±SEM (n=3). ^*p<0.05. NS, not significant. TUBB3, class III β-tubulin; SEM, standard error of the mean.