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. Author manuscript; available in PMC: 2013 Feb 19.
Published in final edited form as: Matrix Biol. 2011 Sep 24;31(1):57–65. doi: 10.1016/j.matbio.2011.09.001

Fig. 2.

Fig. 2

Leiomyoma tissue specimens have an increased pseudo-dynamic modulus compared to myometrial tissue samples. a: Summary of mechanical testing in matched surgical specimens. The pseudo-dynamic modulus (megapascals (MPa) per millimeter (mm) over mm, black diamonds) was increased in leiomyomata (L) surgical samples (n=10) relative to myometrium (M; n=7). Mean pseudo-dynamic moduli (open black squares) for myometrium and leiomyomata were 48.1±25.6 and 202.7±27.8 respectively (p<0.001). b: Leiomyoma surgical samples (n=10) held an increased peak stress (black diamonds) compared to myometrium (n=7). Mean peak stress (open black squares) for myometrium and leiomyomata were 1.35±0.70 and 6.96±0.91 respectively (p<0.001). c: Leiomyoma surgical samples (n=10) contained more sulfated glycosaminoglycan (sGAG) (DMMB assay) relative to matched myometrial samples, n=7: Leiomyoma=0.62±0.080 μg of sGAG per μg of DNA; Myometrium=0.19±0.012 μg per μg, p<0.0001. d: Leiomyoma surgical samples contained more collagen (Hydroxyproline assay) relative to matched myometrium: Leiomyoma=246.7±26.2 μg of collagen per μg of DNA; Myometrium=97.5±18.7 μg per μg, p<0.001. Values are reported as means±SEM. All statistical tests used a 2-tailed unpaired t-Test for unequal variance.