Table 1.
Summary of hypermetabolic response modulators
| Drug | Inflammatory response | Cardiac work | Hepatic steatosis | Protein balance | Insulin resistance/hyperglycemia | Wound healing |
|---|---|---|---|---|---|---|
| Propranolol | Decreased | Decreased | Decreased | Improved | Reduced | Improved |
| Insulin | Decreased | No change | Decreased | Improved | Reduced | Improved |
| Testosterone | Unknown | Unknown | Unknown | Improved | Unknown | Unknown |
| Oxandrolone | Decreased | Improved | No change | Improved | No change | Improved |
| rhGH | Decreased | No change | Unknown | Improved | Increased | Improved |
| IGF/IGFBP-3 | Decreased | No change | Unknown | Improved | Reduced | Improved |
| Fenofibrate | No change | No change | Unknown | No change | Reduced | Improved |
| Metformin | Unknown | Unknown | Unknown | Improved | Reduced | Unknown |
| GLP-1 | Unknown | Unknown | Unknown | Unknown | Reduced | Unknown |
| Ketoconazole | No change | No change | No change | Unknown | Unknown | Unknown |