Cell viability after ALA-SDT. (A) The survival rates of THP-1 macrophages after 5 minutes ultrasound exposure with ALA concentrations at 0, 0.1, 0.2, 0.5, 1.0, and 2.0 mM as determined by MTT assay. (B) The survival rates of THP-1 macrophages after 1 mM ALA incubation with ultrasound exposure for 0, 1, 3, 5, 10, and 15 minutes.
Note: Data represent the means ± SD (n = 6 per group).
Abbreviations: ALA, 5-aminolevulinic acid; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; SD, standard deviation; SDT, sonodynamic therapy.