Fundus photographs of rabbit eye at 3 days (3d), 2 weeks (2wk), 5 weeks (5wk), and 9 weeks (9wk) postinjection of cov-OPS:DNR particles. The oxidized porous silicon particles contained daunorubicin covalently attached to the inner pore walls as described in the text. Initially, the OPS particles appear red due to the presence of daunorubicin. The image obtained at 9 weeks shows significantly fewer particles with a less intense red color, indicative of particle degradation and drug release.