TABLE 1.

Quantitative analysis of PrP^a and PrP^b fibrils generated under unseeded and seeded conditions

The width and length (expressed in nm ± S.E.) of fibrils from the six samples depicted in Fig. 8 were determined.

	PrPa fibrils			PrPb fibrils
	Unseeded	Fast seeds	Slow seeds	Unseeded	Fast seeds	Slow seeds
No. of fibrils analyzed	21	27	23	15	18	20
Fibril width narrow region	10.7 ± 0.8	9.6 ± 0.6	8.8 ± 0.6	10.2 ± 0.6	14.5 ± 0.7 (uniform width)	8.4 ± 0.4
Fibril width wide region	23.3 ± 0.8	20.7 ± 1.1	19.5 ± 1.1	19.2 ± 1.1	14.5 ± 0.7 (uniform width)	20.0 ± 1.1
Fibril length	821 ± 126	681 ± 82	602 ± 67	616 ± 86	102 ± 13	332 ± 58