TABLE 1.

mRNA expression levels of anti-oxidant enzymes

Digital gene expression analysis of anti-oxidant enzymes in liver is shown. The data are taken from the EntrezGene ID gene list from the supplementary material in Pewzner-Jung et al. (11). Results are -fold change of mRNA levels of CerS2 null mice versus WT, n = 3; p values are in parentheses.

Protein	Gene annotation	-Fold change (null versus WT)
		14 days old	30 days old
Glutathione peroxidase 4	Gpx4	NDa	2.27 (<0.1)
Glutathione peroxidase 7	Gpx7	1.54 (<0.05)	2.56 (<0.005)
Glutathione peroxidase 3	Gpx3	5.62 (<0.001)	6.46 (<0.001)
Glutathione S-transferase mu 1	Gstm1	2.29 (<0.05)	2.32 (<0.001)
Glutathione S-transferase pi 1	Gstp1	ND	4.60 (<0.001)
Superoxide dismutase 1, soluble	Sod1	ND	1.86 (<0.001)

^a Not detected.