TABLE 2.
mtDNA point mutations analysis
Skeletal muscle of 6-month-old wild-type and Dm-dNK+/− mice was analyzed.
| Mouse (genotype) |
mt-Cytb gene |
Noncoding control region |
||
|---|---|---|---|---|
| Number of mutations/base pairs sequenced | Mutation frequency (per 10 kb) | Number of mutations/base pairs sequenced | Mutation frequency (per 10 kb) | |
| Wild type 1 | 0/5838 | 0.0 | 2/7567 | 2.6 |
| Wild type 2 | 1/5004 | 2.0 | 3/7567 | 3.9 |
| Wild type 3 | 2/6672 | 3.0 | 2/7567 | 2.6 |
| Dm-dNK+/− 1 | 3/5838 | 5.1 | 2/7567 | 2.6 |
| Dm-dNK+/− 2 | 1/3336 | 3.0 | 2/8648 | 2.3 |
| Dm-dNK+/− 3 | 7/5004 | 14.0 | 1/8648 | 1.2 |