TABLE 2.
Inhibition of DNA gyrases from S. aureus, E. coli, and M. tuberculosis by diospyrin and 7-methyljuglone
| Compound | IC50 for gyrase supercoiling inhibition |
||
|---|---|---|---|
| S. aureus | E. coli | M. tuberculosis | |
| μm | μm | μm | |
| Diospyrin | 8 | 4 | 15 |
| 7-Methyljuglone | 60 | 30 | 30 |
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