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. 2011 Nov 29;39(2):436–448. doi: 10.1093/schbul/sbr165

Table 3.

Tests of Fixed Effects in Mixed-Effects Model Repeated Measures ANOVA for Measures of Psychopathology, Substance Use, Functioning, Quality of Life, and Medication Adherence

Effect F test df P Effect F test df P
Symptoms Substance use
    BPRS total scorea     AUDITa
        Group 0.07 174.6 .786         Group 0.01 183.2 .918
        Time 2.23 5122.6 .055         Time 1.30 5130.1 .272
        Group × time 1.13 5122.6 .347         Group × time 0.73 5130.1 .603
    BPRS positive symptomsa     SDSa
        Group 2.41 180.4 .124         Group 0.42 176.6 .517
        Time 1.55 5148.5 .178         Time 1.75 5118.3 .128
        Group × time 0.41 5148.5 .844         Group × time 0.60 5118.3 .703
    SANSa     ASSIST alcohol
        Affect         Group 0.44 180.72 .509
            Group 0.30 177.8 .589         Time 0.56 5154.1 .729
            Time 1.45 5130.9 .209         Group × time 1.47 5154.1 .204
            Group × time 1.14 5130.9 .342     ASSIST Cannabis
        Alogia         Group 0.35 179.8 .558
            Group 3.00 176.5 .089         Time 0.75 5140.9 .588
            Time 4.06 5214.1 .002         Group × time 0.33 5140.9 .896
            Group × time 4.15 5214.1 .001 Functioning
        Avolition     SOFAS
            Group 0.52 180.0 .475         Group 0.80 179.1 .374
            Time 1.59 5148.1 .168         Time 2.52 5128.4 .033
            Group × time 1.70 5148.1 .137         Group × time 2.30 5128.4 .049
        Anhedonia Quality of life
            Group 0.02 178.9 .879     Physical
            Time 2.62 5144.8 .027         Group 1.00 176.4 .320
            Group × time 1.50 5144.8 .191         Time 0.79 5135.9 .556
        Attention         Group × time 0.63 5135.9 .676
            Group 2.20 178.1 .142     Psychological
            Time 0.40 5154.2 .849         Group 1.41 175.9 .239
            Group × time 2.71 5154.2 .023         Time 1.90 5124.5 .100
    Summaryb         Group × time 0.81 5124.5 .545
        Group 1.38 180.6 .243     Social relationships
        Time 2.11 5185.5 .066         Group 0.58 176,1 .450
        Group × time 2.28 5185.5 .049         Time 1.05 5142.4 .392
    MADRSa         Group × time 1.16 5142.4 .331
        Group 1.02 172.5 .316     Environment
        Time 16.63 5165.9 <.001         Group 1.21 176.1 .275
        Group × time 1.02 5165.9 .406         Time 0.75 5138.1 .591
    SUMD         Group × time 0.56 5138.1 .732
        Awareness of disorder (past and current) Medication adherencea
            Group 0.04 170.4 .840     Group 0.03 165.2 .866
            Time 1.75 5154.9 .127     Time 2.59 5109.8 .030
            Group × time 0.76 5154.9 .583     Group × time 2.35 5109.8 .045
        Awareness of medication (past and current)
            Group 0.48 1, 71.0 .492
            Time 1.15 5, 145.3 .336
            Group × time 1.29 5, 145.3 .273

Note: BPRS, Brief Psychiatric Rating Scale; SANS, Schedule for the Assessment of Negative Symptoms; SUMD, Scale for Unawareness of Mental Disorders; MADRS, Montgomery Asberg Depression Rating Scale; AUDIT, Alcohol Use Disorders Identification Test; SDS, Severity of Dependence Scale; ASSIST, Alcohol, Smoking and Substance Involvement Screening Test; SOFAS, Social and Occupational Functioning Assessment Scale. Bold values indicate significant effects ( P < .05).

a

Analyses based on logarithmic (plus constant)-transformed data due to extreme positive skewness.

b

Summary score was computed by summing the 5 global items of the SANS.