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HE misdetection. (A) pan-CK staining of a lymph node shows several isolated tumor cells (×40). (B) EMA staining of the corresponding lymph node shows several isolated tumor cells (×40). (C) HE staining of the corresponding lymph node shows no clearly visible tumor cells in the lymph node (×40). HE, hematoxylin and eosin; pan-CK, pan-cytokeratin; EMA, epithelial membrane antigen. Arrows indicate isolated tumor cells.
