Table II.
Association between the XRCC1 polymorphism and clinicopathological characteristics.
| No. of cases (n=130)a
|
|||||
|---|---|---|---|---|---|
| Variables | No. (%) | GG (n=63) | AG (n=37) | AA (n=30) | χ2; P-value |
| Age group | |||||
| ≤50 | 48 (36.9) | 14 | 20 | 14 | 11.73; 0.002 |
| >50 | 82 (63.1) | 49 | 17 | 16 | |
| Gender | |||||
| Female | 54 (41.54) | 22 | 12 | 20 | 10.20; 0.006 |
| Male | 76 (58.46) | 41 | 25 | 10 | |
| Dwelling | |||||
| Rural | 91 (70.0) | 36 | 33 | 22 | 11.61; 0.003 |
| Urban | 39 (30.0) | 27 | 4 | 8 | |
| Smoking status | |||||
| Ever | 81 (62.3) | 41 | 23 | 17 | 0.61; 0.737 |
| Never | 49 (37.7) | 22 | 14 | 13 | |
| Tumor location | |||||
| Colon | 52 (40.0) | 17 | 22 | 13 | 10.42; 0.005 |
| Rectum | 78 (60.0) | 46 | 15 | 17 | |
| Nodal status | |||||
| Involved | 88 (67.7) | 50 | 18 | 20 | 10.08; 0.006 |
| Not involved | 42 (32.3) | 13 | 19 | 10 | |
| Tumor grade | |||||
| WD | 98 (75.4) | 48 | 28 | 22 | 0.09; 0.956 |
| MD+PD | 32 (24.6) | 15 | 9 | 8 | |
a
One was squamous cell carcinoma. Significant P-values are shown in bold. WD, well-differentiated; MD, moderately differentiated; PD, poorly differentiated.