Table 2.
Unadjusted and least-square adjusted mean concentrations (standard error) of lipids and apolipoprotein B among adults aged ≥20 years, by glycemic status and survey, National Health and Nutrition Examination Surveys 1988–1991 and 2005-2006
| |
Diagnosed diabetes |
Undiagnosed diabetes |
Prediabetes |
Normal |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | |
| N |
207 |
457 |
|
92 |
103 |
|
566 |
850 |
|
2337 |
2539 |
|
|
Unadjusted |
|
|
|
|
|
|
|
|
|
|
|
|
| Total cholesterol (mg/dl) |
215.0 (3.6) |
181.0 (2.3) |
<0.001 |
223.0 (5.0) |
200.4 (4.8) |
0.002 |
218.0 (1.7) |
202.9 (1.8) |
<0.001 |
200.5 (1.4) |
195.0 (0.9) |
0.002 |
| High-density lipoprotein cholesterol (mg/dl) |
49.1 (1.6) |
50.7 (1.0) |
0.390 |
44.9 (1.8) |
47.7 (1.6) |
0.234 |
48.0 (0.7) |
53.6 (0.7) |
<0.001 |
51.8 (0.7) |
55.7 (0.4) |
<0.001 |
| Low-density lipoprotein cholesterol (mg/dl) |
135.4 (2.9) |
100.5 (1.8) |
<0.001 |
143.3 (3.8) |
121.7 (4.3) |
<0.001 |
142.6 (1.8) |
122.3 (1.4) |
<0.001 |
124.8 (1.3) |
115.4 (0.9) |
<0.001 |
| Non-high-density lipoprotein cholesterol (mg/dl) |
166.0 (4.4) |
130.3 (2.0) |
<0.001 |
178.1 (4.6) |
152.7 (4.4) |
<0.001 |
170.0 (1.8) |
149.3 (1.8) |
<0.001 |
148.8 (1.5) |
139.3 (1.0) |
<0.001 |
| Triglycerides (mg/dl)† |
153.1 (9.8) |
148.9 (4.0) |
0.687 |
173.6 (10.1) |
155.4 (10.1) |
0.207 |
137.0 (4.2) |
136.9 (3.6) |
0.985 |
119.6 (3.6) |
119.5 (1.7) |
0.974 |
| Triglycerides (mg/dl)‡ |
137.8 (9.7) |
133.0 (3.6) |
0.634 |
158.4 (9.2) |
135.0 (9.4) |
0.084 |
122.0 (3.5) |
122.1 (2.9) |
0.970 |
104.3 (3.2) |
104.6 (1.6) |
0.933 |
| Apolipoprotein B (mg/dl) |
114.2 (2.7) |
96.3 (1.5) |
<0.001 |
120.3 (3.4) |
110.4 (3.1) |
0.035 |
115.6 (1.3) |
106.2 (1.2) |
<0.001 |
102.0 (0.9) |
98.6 (0.8) |
0.011 |
|
Age-adjusted |
|
|
|
|
|
|
|
|
|
|
|
|
| Total cholesterol (mg/dl) |
206.7 (3.5) |
172.3 (2.5) |
<0.001 |
215.2 (4.5) |
191.3 (4.7) |
0.001 |
211.0 (1.7) |
195.9 (1.8) |
<0.001 |
202.9 (1.4) |
197.0 (0.8) |
<0.001 |
| High-density lipoprotein cholesterol (mg/dl) |
47.5 (1.6) |
49.1 (1.0) |
0.418 |
43.4 (1.7) |
46.0 (1.6) |
0.265 |
46.7 (0.7) |
52.3 (0.7) |
<0.001 |
52.2 (0.7) |
56.0 (0.4) |
<0.001 |
| Low-density lipoprotein cholesterol (mg/dl) |
130.2 (2.8) |
95.1 (2.0) |
<0.001 |
138.5 (3.7) |
116.0 (4.3) |
<0.001 |
138.3 (1.8) |
118.0 (1.5) |
<0.001 |
126.3 (1.3) |
116.7 (0.8) |
<0.001 |
| Non-high-density lipoprotein cholesterol (mg/dl) |
159.2 (4.3) |
123.3 (2.2) |
<0.001 |
171.8 (4.3) |
145.2 (4.3) |
<0.001 |
164.3 (1.9) |
143.7 (1.8) |
<0.001 |
150.7 (1.5) |
141.0 (0.9) |
<0.001 |
| Triglycerides (mg/dl)† |
145.1 (9.6) |
140.5 (4.2) |
0.662 |
166.1 (9.8) |
146.6 (9.7) |
0.160 |
130.2 (4.4) |
130.1 (3.5) |
0.993 |
121.9 (3.6) |
121.5 (1.6) |
0.912 |
| Triglycerides (mg/dl)‡ |
127.9 (8.9) |
123.0 (3.6) |
0.601 |
147.7 (8.3) |
124.3 (8.3) |
0.052 |
114.5 (3.3) |
114.7 (2.5) |
0.957 |
106.5 (3.2) |
106.5 (1.5) |
1.000 |
| Apolipoprotein B (mg/dl) |
109.9 (2.7) |
91.9 (1.6) |
<0.001 |
116.3 (3.2) |
105.7 (3.1) |
0.024 |
112.0 (1.3) |
102.6 (1.2) |
<0.001 |
103.2 (0.9) |
99.7 (0.7) |
0.006 |
|
Adjusted for age, gender, race or ethnicity, education, and body mass index |
|
|
|
|
|
|
|
|
|
|
|
|
| Total cholesterol (mg/dl) |
205.6 (3.3) |
169.6 (2.5) |
<0.001 |
213.0 (4.7) |
187.6 (4.3) |
<0.001 |
211.5 (1.8) |
194.7 (1.9) |
<0.001 |
203.7 (1.3) |
197.0 (0.8) |
<0.001 |
| High-density lipoprotein cholesterol (mg/dl) |
48.1 (1.2) |
52.2 (1.0) |
0.010 |
46.6 (2.0) |
51.1 (2.1) |
0.128 |
46.9 (0.7) |
53.7 (0.7) |
<0.001 |
51.2 (0.6) |
56.0 (0.3) |
<0.001 |
| Low-density lipoprotein cholesterol (mg/dl) |
129.2 (2.6) |
91.8 (1.9) |
<0.001 |
135.1 (4.2) |
110.6 (3.8) |
<0.001 |
138.0 (1.9) |
116.3 (1.5) |
<0.001 |
127.4 (1.3) |
116.8 (0.7) |
<0.001 |
| Non-high-density lipoprotein cholesterol (mg/dl) |
157.5 (3.9) |
117.4 (2.2) |
<0.001 |
166.4 (5.3) |
136.4 (3.7) |
<0.001 |
164.6 (1.9) |
141.0 (1.9) |
<0.001 |
152.6 (1.3) |
141.0 (0.8) |
<0.001 |
| Triglycerides (mg/dl)† |
141.7 (8.2) |
128.2 (4.3) |
0.153 |
156.3 (11.5) |
129.6 (11.4) |
0.100 |
133.0 (3.8) |
125.2 (3.5) |
0.137 |
125.9 (3.2) |
120.9 (1.6) |
0.161 |
| Triglycerides (mg/dl)‡ |
124.4 (7.2) |
111.0 (3.3) |
0.078 |
136.3 (10.0) |
108.0 (8.6) |
0.032 |
117.5 (2.7) |
110.1 (2.3) |
0.041 |
110.2 (2.9) |
105.9 (1.4) |
0.179 |
| Apolipoprotein B (mg/dl) | 108.7 (2.5) | 88.0 (1.5) | <0.001 | 112.5 (3.4) | 99.7 (2.8) | 0.005 | 111.8 (1.5) | 100.8 (1.2) | <0.001 | 104.4 (0.9) | 99.8 (0.6) | <0.001 |
*P-values from linear regression analyses.
†Untransformed mean.
‡Geometric mean.