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. 2013 Feb 19;8(2):e56833. doi: 10.1371/journal.pone.0056833

Figure 6. Example of a singlish-interface date and multi-party hub proteins.

Figure 6

Images A and B show the quaternary structure for the singlish-date protein Rab GDP dissociation inhibitor alpha (GDI1, YER136W) binding with two different proteins. Image C shows the quaternary structure for the yeast protein beta 6 subunit of the 20S proteasome (PRE7, YBL041W) binding with multiple proteins at the same time. A: GDI1 (green) binding with GTP-binding protein YPT31/YPT8 (purple). PDB ID of the complex: 3cpj [79], [80]. B: GDI1 (green) binding with GTP-binding proteinYPT1 (yellow). PDB ID of the complex: 1ukv [80], [81]. The protein binds at one location (singlish-interface) with one partner at a time (date). C: PRE7 (green) binds with PUP1 (orange), PUP3 (red), C5 (pink), PRE4 (purple). PDB ID of the complex: 3bdm [80], [82]. The protein binds at multiple locations (multi-interface) with many partners at same time (party).