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. 2013 Feb 19;8(2):e56613. doi: 10.1371/journal.pone.0056613

Table 1. Clinicopathological characteristics and Kaplan-Meier cause specific survival (CSS) analysis of SEER hypopharyngeal cancer cases with pathological lymph node involvement.

Variables No. 5-year CSS Log-rank χ2 P value
Race 29.840 <0.001
White 696 46.2%
Black 155 26.7%
Other 65 37.5%
Gender 0.303 0.582
Male 750 41.7%
Female 166 44.8%
Year of diagnosis 0.156 0.925
1988–1994 282 42.1%
1995–2001 298 43.1%
2002–2008 336 41.4%
Primary site 17.637 0.003
Pyriform sinus 664 43.2%
Postcricoid region 20 28.7%
Aryepiglottic fold 25 63.4%
Posterior wall 36 42.0%
Overlapping lesion 24 13.8%
Hypopharynx, NOS 147 42.1%
Histological grade 3.230 0.520
I 28 36.5%
II 370 44.6%
III 406 40.8%
IV 16 0
Unknown 96 39.9%
Surgery of primary site 1.317 0.725
None 216 40.0%
Local excision 92 48.4%
Pharyngectomy 595 42.4%
Unknown 13 0
Radiation sequence 25.588 <0.001
No radiation 226 34.5%
Pre-operative 50 35.1%
Post-operative 620 46.1%
Other 20 0
Cancer directed surgery 7.519 0.006
Yes 747 43.2%
Other 169 38.9%
T stage 38.547 <0.001
T1 81 65.9%
T2 152 56.1%
T3 144 39.6%
T4 376 33.2%
Tx 163 41.8%
N stage 15.483 <0.001
N1 194 51.4%
N2 653 41.5%
N3 69 23.0%
M stage 46.848 <0.001
M0 871 43.8%
M1 31 5.4%
Mx 14 24.2%