Table 2. Multivariate analysis of the LNR and covariates associated with SEER cancer cause-specific survival of hypopharyngeal cancer cases with lymph node metastasis.

Variables	HR (95% CI)	P value
Race (White as reference)
Black	1.678(1.334–2.112)	<0.001
Other	1.392(0.999–1.940)	0.051
Primary site (Pyriform sinus as reference)
Postcricoid region	1.088(0.619–1.911)	0.769
Aryepiglottic fold	0.664(0.338–1.305)	0.235
Posterior wall	2.327(1.459–3.711)	<0.001
Overlapping lesion	2.140(1.327–3.453)	0.002
Hypopharynx, NOS	1.206(0.935–1.555)	0.149
Radiation sequence (no radiation as reference)
Pre-operative	0.976(0.642–1.482)	0.908
Post-operative	0.643(0.512–0.807)	<0.001
Other	1.060(0.580–1.936)	0.850
T classification (T1 as reference)
T2	1.441(0.906–2.292)	0.122
T3	2.504(1.597–3.925)	<0.001
T4	2.965(1.954–4.497)	<0.001
Tx	1.671(1.055–2.648)	0.029
N classification (N1 as reference)
N2	1.352(1.064–1.717)	0.014
N3	2.224(1.544–3.202)	<0.001
M classification (M0 as reference)
M1	4.195(2.679–6.569)	<0.001
MX	1.289(0.636–2.613)	0.482
No. of regional lymph node examined	1.009(1.003–1.014)	0.002
LNR as continuous variable	2.415(1.707–3.416)	<0.001
Age	1.017(1.007–3.416)	<0.001