Table 5. Different staging systems for SEER cause-specific survival (CSS) and overall survival (OS) of SEER patients with hypopharyngeal cancer.
| Staging system | No. | 5/10/15-y CSS(%) | log-rank χ2 † | HR (95% CI) ‡ | C-index‡ | AIC‡ | 5/10/15-y OS(%) | log-rank χ2# | HR (95% CIs) * | C-index* | AIC* |
| N classification | 41.026 | 0.683 | 7359.73 | 22.437 | 0.657 | 10428.44 | |||||
| N0 | 236 | 64.7/45.7/40.3 | Reference | 47.3/24.5/12.4 | Reference | ||||||
| N1 | 194 | 51.4/35.6/22.8 | 1.406(1.048–1.887) | 38.8/19.2/11.2 | 1.134(0.901–1.439) | ||||||
| N2 | 653 | 41.5/34.1/26.5 | 1.926(1.523–2.435) | 29.8/19.0/9.6 | 1.515(1.266–1.812) | ||||||
| N3 | 69 | 23.0/23.0/23.0 | 2.869(1.984–4.148) | 15.8/15.8/10.6 | 1.954(1.422–2.683) | ||||||
| R classification | 61.697 | 0.686 | 7352.23 | 49.499 | 0.661 | 10417.85 | |||||
| R0 | 236 | 64.7/45.7/40.3 | Reference | 47.3/24.5/12.4 | Reference | ||||||
| R1∶0–0.05 | 177 | 55.6/45.4/41.3 | 1.256(0.930–1.698) | 43.1/24.7/18.1 | 1.072(0.850–1.352) | ||||||
| R2∶0.05–0.30 | 458 | 43.6/33.3/22.5 | 1.922(1.507–2.452) | 31.6/20.7/8.1 | 1.470(1.218–1.775) | ||||||
| R3: >0.30 | 281 | 30.7/25.8/16.9 | 2.497(1.882–3.314) | 21.3/11.0/6.4 | 1.952(1.556–2.448) |
†
The P value for Log-rank χ2 tests of cause specific survival was less than 0.001.
‡
Being calculated using the multivariates Cox regression model for cause specific survival with either N classification or R classification and variates listed at Table 4 as covariates.
#
The P value for Log-rank χ2 tests of overall survival was less than 0.001.
*
Being calculated using the multivariates Cox regression model for overall survival with N classification or R classification and variates listed at Table 4 as covariates.