Table 1.
Author/year | Drug(s) | Dose (mg) | Age/sex | Weight (kg) | Time to ECPB (h) | ECPB technique | Time on ECPB (h) | Outcome |
---|---|---|---|---|---|---|---|---|
Hendren et al. (1989) | Verapamil SR | 1,440 | 2/M | 13.5 | Unknown | Unknown | 3.75 | Died 29 h post-OD |
Yasui et al. (1997) | Flecainide | Unknown | 20/F | Unknown | 2.5 after OD | VA femoral | 10 | Died 10 days post-OD; brain damage and renal failure |
2 after arrival | ||||||||
Berhinger et al. (1998) | Digoxin | 10 | 79/M | Unknown | 5.17 from OD | VA femoral | 4 | Died 12 days post-OD; ARDS and septic shock |
0.37 from admission | ||||||||
Holzer et al. (1999) | Verapamil | 4,800–6400 | 60/M | 60 | 8.10 from OD | VA femoral | 5.5 | Full recovery |
3.5 from admission | ||||||||
Corkeron et al. (1999) | Flecainide | 4,000 | 20/F | Unknown | 5.15 from OD | VA femoral | 30 | Full recovery |
5.0 from admission | ||||||||
Pasic et al. (2000) | Prajmalium bitartrate | 320 | 25/F | Unknown | 1.30 from OD | Ascending aorta | 16.75 | Mild ataxia, discharged 35 days post-OD |
Durward et al. (2003) | Diltiazem SR | 12,000 | 16/F | 50 | 17 from OD | Right atrium; aorta | 48 | Full recovery |
10 from admission | ||||||||
MacLaren et al. (2004) | Verapamil SR | 7,200 | 45/F | Unknown | Unknown | VA femoral | 144 | Full recovery |
Doxepin | 1,600 | |||||||
Quetiapine | 10,000 | |||||||
Diazepam | 2,000 | |||||||
Clonazepam | 100 | |||||||
Temazepam | 200 | |||||||
Kolcz et al. (2007) | Verapamil SR | 960 | 15/F | 60 | 2 from admission | Right atrium; aorta | 70 | Full recovery |
Propanolol | 550 | |||||||
Marciniak et al. (2007) | Ibuprofen | 10,000 | 14/M | 75 | 7 from OD | VA carotid; internal jugular | 96 | Full recovery |
Shenoi et al. (2011) | Bupropion SR | 9,000 | 11 months/M | 12 | 21 from OD | VA | 71 | Full recovery |
18 from admission |
SR sustained release, M male, F female, OD overdose, VA veno-arterial