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Effects of external MTSES and pH on A107C-CFTR. (A) Whole-cell A107C-CFTR currents in response to external MTSES (left) and I-V curves extracted from the whole-cell recording as marked. (B) Effects of acidic or alkaline pH on the whole-cell A107C-CFTR currents (left). Corresponding I-V relationships were shown on the right. (C) A control experiment on WT/Cysless demonstrating a lack of effect by changes of bath pH.
