Table 1.

Estimated binding free energies (kcal mol⁻¹) for the protein-ligand systems described in this work, and upper and lower bounds of the 68% CI for $\Delta G_b$

Protein	Ligand	With SVD			Without SVD
		$\Delta G_b$	Lower	Upper	$\Delta G_b$	Lower	Upper
Lysozyme	NAG	−2.98	−3.02	−2.94	−7.43	−7.54	−7.33
Lysozyme	(NAG)2	−5.73	−5.80	−5.67	−5.03	−5.04	−5.01
Lysozyme	(NAG)3	−12.82	−14.31	−11.10	−5.14	−5.16	−5.12
Galectin	lactose	−5.47	−5.53	−5.41	−5.08	−5.10	−5.06
ADH	NAD+	−3.86	−3.88	−3.83	−3.93	−3.95	−3.91