FIG. 3.

Survival of HTori-3 cells irradiated with γ -rays and treated with SeM. HTori-3 cells were treated with 5 µM SeM for 16 days starting 2 days prior to the radiation exposure (Groups 2 and 4), 2 days prior to the radiation exposure (Group 5), 14 days starting immediately after the radiation exposure (Group 6), 12 days starting 2 days after the radiation exposure (Group 7), or 7 days starting 1 wk after the radiation exposure (Group 8). The cells in Groups 1 and 2 were sham-irradiated and included as controls whereas the cells in Groups 3 through 8 were irradiated with γ -rays at a single dose of 600 cGy. After the radiation exposure and SeM treatment, the cells were cultured in control medium for an additional 6 wk and then used for the clonogenic survival assay. Each data point represents a mean of 4 replicate flasks. The standard deviation is indicated by the error bars.