Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CDDO-Me inhibits telomerase activity. (A) Measurement of telomerase activity. MiaPaCa-2 and Panc-1 cells were treated with CDDO-Me (0–10 μM) for 48 h and telomerase activity of cell extracts was measured by TRAP assay as described in Section 2. (A and C) DNA laddering patterns under different treatment conditions. (B and D) Quantification of telomerase activity in (A) and (C). Experiments were repeated two times. NC, negative control (no cell extract).
