. Author manuscript; available in PMC: 2013 Feb 20.

Published in final edited form as: Breast Cancer Res Treat. 2011 Aug 12;131(1):197–205. doi: 10.1007/s10549-011-1712-y

Table 3.

Number of methylated genes in relation to all-cause or breast cancer-specific mortality after 8 years of follow-up among a population-based cohort of women diagnosed with breast cancer in 1996-1997, Long Island Breast Cancer Study Project

No of genes Methylated^*	No. of cases	All-cause mortality		Breast cancer-specific mortality

		No. of Death	HR^** (95% CI)	No. of death	HR^** (95% CI)
0-1	149	32	1.00	14	1.00
2-3	329	59	0.76 (0.49-1.16)	30	0.95 (0.50-1.79)
4-5	215	57	1.24 (0.80-1.91)	31	1.61 (0.85-3.02)
6-10	72	24	1.41 (0.83-2.40)	15	2.38 (1.14-4.96)

Data were combined with previously published data (20, 21) on APC and p16.

^**

Adjusted for age at diagnosis as continuous, P_trend = 0.03, HR = 1.21 (95%CI: 1.02-1.43) for all-cause mortality; P_trend = 0.004, HR = 1.41 (95%CI: 1.12-1.78) for breast cancer-specific mortality