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APRPG-modified PEGylated liposomes for angiogenic vessel targeting.
Notes: APRPG-PEG-Distearoylphosphatidylethanolamine was synthesized and incorporated into liposomes to prepare APRPG-modified PEGylated liposomes. The APRPG peptide was originally identified by in vivo biopanning using a phage-displayed peptide library. PEGylated liposomes were used as nontargeted control liposomes.
Abbreviations: APRPG, Ala-Pro-Arg-Pro-Gly; PEG, polyethylene glycol.
