Table 2.
Results of specific Cox regression modelsa
| Variables | HR | 95%CI | P-value |
|---|---|---|---|
|
Colon | |||
|
Age | |||
| <45 years (Ref) |
- |
- |
- |
| 45-65 years |
0.52 |
0.33 - 0.81 |
0.01 |
| >65 years |
0.65 |
0.43 - 0.97 |
0.03 |
|
Gender |
|
|
|
| Female (Ref) |
- |
- |
- |
| Male |
0.74 |
0.52 - 1.05 |
0.10 |
|
Grade | |||
| Grade I (Well diff) (Ref) |
- |
- |
- |
| Grade II (Mod diff) |
0.72 |
0.39 - 1.34 |
0.30 |
| Grade III (Poor diff) |
0.66 |
0.43 - 1.01 |
0.06 |
| Grade IV (Undiff Anaplastic) |
1.12 |
0.63 - 2.01 |
0.68 |
| Unknown |
0.55 |
0.13 - 2.37 |
0.42 |
|
Extension | |||
| Localized (Ref) |
- |
- |
- |
| Regional: Direct Ext |
0.45 |
0.18 - 1.11 |
0.08 |
| Regional: Lymph Node |
0.65 |
0.28 - 1.51 |
0.32 |
| Regional: Dir Ext and Lymph Node |
0.81 |
0.25 - 2.58 |
0.72 |
| Regional NOS |
1.44 |
0.66 - 3.15 |
0.35 |
| Distant Metastasis |
2.53 |
1.17 - 5.45 |
0.01 |
|
Recto-sigmoid | |||
|
Age | |||
| <45 years (Ref) |
- |
- |
- |
| 45-65 years |
0.53 |
0.19 - 1.46 |
0.22 |
| >65 years |
0.61 |
0.26 - 1.41 |
0.25 |
|
Gender | |||
| Female (Ref) |
- |
- |
- |
| Male |
1.07 |
0.45 - 2.55 |
0.86 |
|
Grade | |||
| Grade I (Well diff) (Ref) |
- |
- |
- |
| Grade II (Mod diff) |
0.85 |
0.19 - 3.73 |
0.83 |
| Grade III (Poor diff) |
0.55 |
0.21 - 1.48 |
0.24 |
| Grade IV (Undiff Anaplastic) |
0.88 |
0.20 - 3.84 |
0.86 |
|
Extent | |||
| Localized (Ref) |
- |
- |
- |
| Regional: Direct Ext |
0.74 |
0.07 - 7.41 |
0.79 |
| Regional: Lymph Node |
1.83 |
0.17 - 18.95 |
0.61 |
| Regional: Dir Ext and Lymph Node |
2.12 |
0.21 - 20.94 |
0.52 |
| Regional NOS |
2.13 |
0.21 - 21.84 |
0.52 |
| Distant Metastasis |
5.74 |
0.67 - 49.01 |
0.11 |
|
Rectum | |||
|
Age |
|
|
|
| <45 years (Ref) |
- |
- |
- |
| 45-65 years |
0.66 |
0.41 - 1.05 |
0.08 |
| >65 years |
0.72 |
0.48 - 1.08 |
0.11 |
|
Gender | |||
| Female (Ref) |
- |
- |
- |
| Male |
0.66 |
0.45 - 0.98 |
0.04 |
|
Grade | |||
| Grade I (Well diff) (Ref) |
- |
- |
- |
| Grade II (Mod diff) |
0.63 |
0.32 - 1.21 |
0.16 |
| Grade III (Poor diff) |
0.78 |
0.48 - 1.29 |
0.34 |
| Grade IV (Undiff Anaplastic) |
1.52 |
0.80 - 2.87 |
0.19 |
| Unknown |
0.75 |
0.09 - 6.04 |
0.79 |
|
Extension | |||
| Localized (Ref) |
- |
- |
- |
| Regional: Direct Ext |
1.11 |
0.49 - 2.51 |
0.79 |
| Regional: Lymph Node |
1.01 |
0.42 - 2.45 |
0.97 |
| Regional: Dir Ext and Lymph Node |
0.86 |
0.33 - 2.24 |
0.75 |
| Regional NOS |
1.48 |
0.63 - 3.47 |
0.36 |
| Distant Metastasis |
3.92 |
0.46 - 33.25 |
0.21 |
| Unknown | 3.70 | 1.66 - 8.24 | 0.01 |
Abbreviations: CI, confidence interval; Diff, differentiation; Dir, direct; Ext, extent; HR, hazard ratio; Mod, moderate; NOS, not otherwise specified; Ref, reference, Undiff, undifferentiated.