Table 3.
Summary of contractile parameters at baseline in all groups
| Sham (n = 6) | TAC (n = 7) | Ctrl (n = 6) | l-NAME (n = 5) | |
|---|---|---|---|---|
| AT (mN mm−2) | 15 ± 2 | 16 ± 4 | 18 ± 3 | 23 ± 8 |
| dT/dtmax (mN mm−2 s−1) | 141 ± 35 | 198 ± 53 | 199 ± 20 | 230 ± 81 |
| dT/dtmin (mN mm−2 s−1) | −71 ± 10 | −99 ± 20 | −112 ± 9 | −115 ± 39 |
| PS (%Lmax) | 0.1 ± 0.01 | 0.08 ± 0.01 | 0.08 ± 0.01 | 0.1 ± 0.01 |
| dL/dtmax (Lmax s−1) | 1.5 ± 0.1 | 1 ± 0.1 | 1 ± 0.1 | 1 ± 0.1 |
| dL/dtmin (Lmax s−1) | −1.7 ± 0.3 | −1.3 ± 0.2 | −1.2 ± 0.2 | −1.2 ± 0.2 |
| tHR (ms) | 292 ± 34 | 257 ± 16 | 265 ± 21 | 318 ± 19* |
All data are means ± SEM. AT, active tension; dT/dtmax, maximal velocity of tension rise; dT/dtmin, maximal velocity of tension decline; PS, peak isotonic shortening; dL/dtmax, maximum velocity of shortening; dL/dtmin, maximum velocity of lengthening; tHR, time to half relaxation; *P < 0.05 vs. Ctrl.