Table 1. Serum microRNAs differentially expressed in AML samples compared to normal controls.
miRNA | training set | validation set | training+validation | |||
Fold change (mean±SE;AML/normal) | p-value | Fold change (mean±SE;AML/normal) | p-value | Fold change (mean±SE;AML/normal) | p-value | |
miR-10a-5p | 3.81±0.29 | 4.98×10−13 | 2.23±0.27 | 2.34×10−5 | 2.55±0.22 | 8.16×10−10 |
miR-93-5p | 3.40±0.14 | 1.12×10−18 | 4.48±0.34 | 4.78×10−20 | 4.11±0.24 | 5.76×10−28 |
miR-129-5p | 3.28±0.29 | 5.84×10−10 | 3.46±0.20 | 5.90×10−22 | 3.41±0.16 | 2.24×10−29 |
miR-155-5p | 6.11±0.73 | 2.69×10−9 | 4.42±0.20 | 1.05×10−37 | 4.79±0.23 | 6.73×10−39 |
miR-181b-5p | 2.29±0.29 | 7.00×10−5 | 2.27±0.21 | 8.17×10−7 | 2.31±0.17 | 2.42×10−10 |
miR-320d | 7.60±0.88 | 3.37×10−10 | 5.02±0.29 | 8.17×10−7 | 5.53±0.29 | 1.22×10−33 |
miR-22-3p | 3.24±0.27 | 1.56×10−11 | 1.54±0.32 | 3.52×10−9 | ||
miR-129-3p | 2.18±0.13 | 2.15×10−12 | 1.38±0.37 | 2.17×10−25 | ||
miR-139-5p | 4.85±0.47 | 5.77×10−11 | 1.81±0.15 | 7.55×10−15 | ||
miR-375 | 3.08±0.29 | 1.23×10−8 | 1.42±0.19 | 4.32×10−8 | ||
miR-485-5p | 4.26±0.53 | 8.06×10−8 | 1.63±0.28 | 6.33×10−4 |