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. 2013 Feb 20;8(2):e57375. doi: 10.1371/journal.pone.0057375

Figure 3. Effect of intraperitoneal or oral administration of OC on serum GLP-1 concentration.

Figure 3

(A) Mice were deprived of food for 5 h and then injected intraperitoneally with saline (control) or the indicated doses of recombinant ucOC, of GlaOC. Blood was collected 20 min later for determination of the serum concentration of GLP-1. Part of mice was orally administered with sitagliptin (1 µg/kg) 30 min before injection of OC. (B) Mice deprived of food for 5 h were treated orally with saline (control) or the indicated doses of ucOC or GlaOC. Blood samples collected 20 min later were assayed for serum GLP-1 concentration. All data are means ± SEM for five to seven mice. *P < 0.05, **P < 0.01 versus control (Student's t test).