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. 2013 Feb 20;8(2):e56657. doi: 10.1371/journal.pone.0056657

Figure 2. IL17 pathway- and IL17+ Th- gene sets in human AR: Segregation of AR and STA.

Figure 2

Genes from the IL17 pathway gene-set (2a) and from the Th17 gene-set (2b) were used for hierarchical clustering of post-transplant biopsies and resulted in clear separation of AR and STA after mean centering arrays and genes (Euclidean Distance, Cosine Dissimilarity). Unsupervised principal component analysis (PCA) of the same samples using the same genes confirmed the separation of AR and STA (2c, d). A separation of the AR group into C4d+ and C4d- cases was not seen.