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. 2013 Feb 20;8(2):e56657. doi: 10.1371/journal.pone.0056657

Figure 3. Fenofibrate gene expression in human PBMC: Fenofibrate regulates IL17 and IFN-γ gene expression in CD3/CD28 stimulated human PBMC.

Figure 3

PBMC from healthy individuals (n = 5) were stimulated with CD3/CD28 antibodies (S) leading to significant upregulation of IL17 and IFN-γ which was inhibited by Fenofibrate (S+FF). Values represent mean fold changes versus non-stimulated (NS) cells plus Standard error of mean calculated using ΔΔCt method and 18S as endogenous control gene; experiments were performed in triplicates. Student T-test for paired data: * p-value <0.05. Individual p-values are displayed in Table 3.