Table 1. Patient Demographics.
Score | D0 | STA | BL | ARIA | ARIB |
Number | 33 | 16 | 4 | 7 | 6 |
Histological diagnosis (Banff) | Pre-transplant donor biopsy | No significant graft abnormalities | Borderline acute rejection | Mild-moderate cellular acute rejection | Severe cellular acute rejection |
% non-protocol | / | 25% | 50% | 57% | 33.3% |
Time post Transplantation [months] | / | 25.4 (+71/−25) | 10.2 (+8/−5) | 12.6 (+19/−7) | 5.8 (+8/−3) |
# C4D | / | 0 | 0 | 2 | 1 |
# CD20 | / | 0 | 0 | 0 | 3 |
Serum Creatinine [mg/mL] | / | 0.5275 | 1.075 | 0.924 | 0.72 |
Recipient age | 8.3 (+10/−6.7) | 16.6 (+2/−4) | 12.3 (+6/−4) | 11.8 (+6/−8) | 13.4(+5/−10) |
Recipient gender [%male] | 75% | 75% | 50% | 28.6% | 66.7% |
Donor age | 29.5(+23/−15) | 31.1 (+16/−17) | 26.5 (+12/−26) | 26.7 (+17.3/−19) | 26.7 (+17/−11) |
Donor gender [%male] | 40.9% | 50% | 50% | 57.1% | 83.3% |
Immunosuppression | / | MMF+Tac (9)/Sir (1)/Aza (1) +/−SB (5)b | MMF+Tac+SB | MMF+Tac (4)/Sir(1)+/−SB (2) | MMF+Tac(2)/Aza(1)+/−SB (3) |
HLA MM a | / | 1.5 | 0 | 0 | 0 |
HLA MM = human leukocyte antigen mismatch;
Sir = Sirolimus; SB = steroid based; Aza = Azathioprine;