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. 2013 Feb 20;8(2):e57012. doi: 10.1371/journal.pone.0057012

Table 1. Characteristics of studies included in the meta-analysis.

Author Juan Zhou WonHee Kim Hikmet Akkiz Teng Xu Xinwei Zhang Yu Xiang
Year 2012 2012 2011 2008 2011 2012
Ethnicity Asian Asian European Asian Asian Asian
Country China Korea Turkey China China China
SNP rs2910164rs3746444 rs2910164rs3746444 rs2910164rs3746444 rs2910164rs3746444 rs2910164 rs2910164
Genotyping method PCR-RFLP PCR-RFLP PCR-RFLP PCR-RFLP PCR-RFLP PCR-RFLP
NO Cases/controls 186/483 159/201 222/222 479/504 925/840 100/100
HWE (rs2910164) 0.056 0.190 0.384 0.119 0.149 0.506
HWE (rs3746444) 0.100 0.278 1.000 0.284
(rs2910164)Cases CC 67 57 10 158 319 28
(rs2910164)Cases CG 86 88 75 241 450 45
(rs2910164)Cases GG 33 14 137 80 156 27
(rs2910164)Controls CC 158 74 11 197 303 33
(rs2910164)Controls CG 254 103 67 249 386 46
(rs2910164)Controls GG 71 24 144 58 151 21
(rs3746444)Cases AA 141 109 45 36
(rs3746444)Cases AG 41 47 87 40
(rs3746444)Cases GG 4 3 90 24
(rs3746444)Controls AA 371 120 45 54
(rs3746444)Controls AG 100 74 93 36
(rs3746444)Controls AG 12 7 82 10

Hardy-Weinberg equilibrium (HWE) was evaluated using the goodness-of-fit chi-square test. P values were presented. P<0.05 was considered representative of a departure from HWE. SNP, single nucleotide polymorphism.