Table 1. Characteristics of studies included in the meta-analysis.
Author | Juan Zhou | WonHee Kim | Hikmet Akkiz | Teng Xu | Xinwei Zhang | Yu Xiang |
Year | 2012 | 2012 | 2011 | 2008 | 2011 | 2012 |
Ethnicity | Asian | Asian | European | Asian | Asian | Asian |
Country | China | Korea | Turkey | China | China | China |
SNP | rs2910164rs3746444 | rs2910164rs3746444 | rs2910164rs3746444 | rs2910164rs3746444 | rs2910164 | rs2910164 |
Genotyping method | PCR-RFLP | PCR-RFLP | PCR-RFLP | PCR-RFLP | PCR-RFLP | PCR-RFLP |
NO Cases/controls | 186/483 | 159/201 | 222/222 | 479/504 | 925/840 | 100/100 |
HWE (rs2910164) | 0.056 | 0.190 | 0.384 | 0.119 | 0.149 | 0.506 |
HWE (rs3746444) | 0.100 | 0.278 | 1.000 | 0.284 | ||
(rs2910164)Cases CC | 67 | 57 | 10 | 158 | 319 | 28 |
(rs2910164)Cases CG | 86 | 88 | 75 | 241 | 450 | 45 |
(rs2910164)Cases GG | 33 | 14 | 137 | 80 | 156 | 27 |
(rs2910164)Controls CC | 158 | 74 | 11 | 197 | 303 | 33 |
(rs2910164)Controls CG | 254 | 103 | 67 | 249 | 386 | 46 |
(rs2910164)Controls GG | 71 | 24 | 144 | 58 | 151 | 21 |
(rs3746444)Cases AA | 141 | 109 | 45 | 36 | ||
(rs3746444)Cases AG | 41 | 47 | 87 | 40 | ||
(rs3746444)Cases GG | 4 | 3 | 90 | 24 | ||
(rs3746444)Controls AA | 371 | 120 | 45 | 54 | ||
(rs3746444)Controls AG | 100 | 74 | 93 | 36 | ||
(rs3746444)Controls AG | 12 | 7 | 82 | 10 |
Hardy-Weinberg equilibrium (HWE) was evaluated using the goodness-of-fit chi-square test. P values were presented. P<0.05 was considered representative of a departure from HWE. SNP, single nucleotide polymorphism.